The fast rhythm of life, frequent stress, bad habits — all this can lead to the appearance of certain problems with potency in a man. Erectile dysfunction is a pathological condition characterized by the inability to achieve an erection sufficient for sexual intercourse. Most often, doctors recommend a comprehensive treatment of this pathology, including not only drugs, but also psychotherapeutic sessions, physiotherapy, and so on. Below we will talk about medication methods to increase potency.

Before considering medicines, we emphasize that before using them, you should consult your doctor. Most often, phosphodiesterase-5 inhibitors are prescribed for the treatment of potency problems, which we will consider.



Sildenafil is considered the most commonly prescribed drug for the treatment of erectile dysfunction. In 2015, scientists from Moscow published a paper, the results of which found that sildenafil is a first-line drug in the treatment of erectile dysfunction.

The mechanism of action of this medication is the release of nitric oxide in the cavernous bodies during intimate stimulation. As a result, smooth muscle fibers relax, blood flow increases, and an erection is achieved.

Studies show that the effect of taking this drug occurs after 30-120 minutes.

Contraindications to its use are:

  • Individual hypersensitivity;
  • Lactose intolerance, lactase deficiency;
  • Age up to 18 years.


Another effective drug, also belonging to the group of phosphodiesterase-5 inhibitors, is vardenafil. It has a similar mechanism of action to sildenafil and is widely used to treat erectile dysfunction.

The main advantage of vardenafil is the rapid onset of the effect (within approximately 15 minutes). At the same time, its action lasts up to 5 hours.

This medication should be taken with caution in people suffering from hypotension. In some cases, it can lead to the development of such side effects as headache, nausea, redness of the face, and so on.


Tadalafil is also widely used to treat various erection problems.

It was developed at the end of the 20th century, it begins to act about half an hour after ingestion.

The main advantages of tadalafil are the absence of a pronounced effect on the level of blood pressure, depending on food intake. Often after using this remedy, side effects such as headache, dyspeptic disorders are observed.


Udenafil is a medication that has the same effect as the above drugs.

The effect of the use of this remedy, on average, occurs within an hour.

It is worth refusing to use udenafil if:

  • Under the age of 18;
  • Individual hypersensitivity;
  • Simultaneous intake of nitrates and other nitric oxide donators;
  • Heart attacks or strokes transferred less than six months ago;
  • Severe violations of the functional activity of the kidneys and so on.

Published on 12.03.2022 19:31

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Used sources

Comparative characteristics of sildenafil and other phosphodiesterase type 5 inhibitors in the treatment of patients with erectile dysfunction (literature review) / Lokshin K.L. // breast cancer 2013 #18

Preserve and strengthen male potential / Shirokova I., Sidorova I. // Remedium. Magazine about the Russian market of medicines and medical equipment 2015 #4

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